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Facial aging is a natural process characterized by the gradual loss of volume, the deepening of folds, and the emergence of fine lines. In the vibrant, professional environment of San Francisco, many individuals seek ways to maintain a refreshed and youthful appearance without the need for invasive surgery. Injectable dermal fillers offer a versatile, non-surgical solution to restore lost volume, enhance facial contours, and smooth away the signs of aging with minimal downtime.

At the practice of Dr. Karen Horton, our aesthetic team, led by Board-Certified Nurse Practitioners Emily Sespaniak (@bayareainjector) and Agnes Wong (@np.agnes), specialize in providing natural-looking results tailored to your unique anatomy. Whether you are looking for subtle lip augmentation or a comprehensive facial rejuvenation, our goal is to enhance your features while maintaining the integrity of your natural expressions.

My face looks amazing! You're the best. I look 10 years younger today. I can't believe the difference in my cheeks/under eye area. You are a miracle worker. ~ C.H.

Why Does the Face Lose Volume?

As we age, the underlying structures of the face undergo significant changes. The primary biological cause of these changes is the depletion of collagen and elastin, the proteins responsible for skin elasticity and firmness. The body’s production of collagen begins to decline in our mid-20s, leading to thinner skin and a loss of structural support.

Furthermore, the fat pads that provide youthful fullness in the cheeks and temples begin to shift or diminish, while bone resorption can alter the foundation of the face. These factors contribute to the development of:

  • Nasolabial folds: The lines running from the nose to the corners of the mouth.
  • Marionette lines: The lines extending downward from the corners of the mouth.
  • Hollow temples and cheeks: Areas where volume loss creates a gaunt appearance.
  • Tear troughs: The under-eye area where shadows and fine lines often appear first.

Our Philosophy: Natural-Looking Results

We believe that the best injectable treatments are the ones that no one notices but help keep you looking fresh, vital and youthful. Our approach centers on “full-facial balancing,” a technique that looks at the face as a whole rather than treating isolated wrinkles. This ensures that every facial non-surgical enhancement is harmonious and subtle.

“My goal is never to change how a patient looks, but rather to restore the youthful contours they once had,” says Emily Sespaniak, NP. “By using a gentle touch and a meticulous eye for detail, we can achieve a refreshed look that feels entirely authentic to the individual.”

Agnes Wong, NP, adds, “Education is a cornerstone of our practice. We take the time to explain the ‘why’ behind every injection site, ensuring our patients feel informed and confident in their personalized treatment plan.”

Agnes Wong, MSN, NP-BC with patient

Comprehensive Range of FDA-Approved Dermal Fillers

We offer a curated selection of the most advanced, FDA-approved fillers to address a wide variety of aesthetic goals. Each product has unique properties, such as different levels of thickness and flexibility, allowing us to choose the perfect tool for each treatment area.

Hyaluronic Acid Fillers

Hyaluronic acid is a naturally occurring substance in the skin that helps maintain hydration, elasticity, and volume. Because it is biocompatible and reversible, it remains the gold standard for non-surgical facial rejuvenation.

  • Restylane-L®: A versatile filler used to smooth moderate to severe facial wrinkles and folds, such as nasolabial folds.
  • Restylane Kysse®: Designed specifically for lip enhancement, providing soft, natural-looking volume while maintaining flexibility and expression.
  • Restylane Refyne® and Restylane Defyne®: Formulated to soften dynamic expression lines while preserving natural facial movement.
  • Restylane Contour®: Developed for cheek enhancement, offering flexible lift and natural-looking midface contour.
  • Restylane Lyft®: A firmer formulation used to restore structure and volume to the cheeks and midface, and also FDA-approved for use in the hands.
  • JUVÉDERM® Voluma® XC: Used to restore volume in the cheeks and midface, improving contour and structural support.
  • JUVÉDERM® Vollure® XC: Designed to soften moderate to severe facial folds while allowing for natural expression.
  • JUVÉDERM® Ultra® XC: Commonly used for lip enhancement and smoothing moderate facial lines.

Collagen-Stimulating Injectables

  • Sculptra®: A biostimulatory injectable composed of poly-L-lactic acid (PLLA). Rather than providing immediate volume alone, Sculptra works gradually by stimulating your body’s natural collagen production, improving skin structure, contour, and overall firmness over time.

Skin Quality Enhancers

  • SKINVIVE™ by JUVÉDERM®: A microdroplet hyaluronic acid injectable designed to improve skin smoothness and hydration in the cheeks. Unlike traditional fillers, it enhances overall skin quality and radiance without adding significant volume.

Common Treatment Areas for Dermal Fillers

Dermal filler treatment can be used to address multiple areas of the face to create a more youthful appearance:

  • Cheek Enhancement: Restoring volume to the midface to lift the lower face and reduce the appearance of nasolabial folds.
  • Lip Augmentation: Adding subtle volume, defining the borders, and smoothing fine lines around the mouth.
  • Jawline and Chin Contouring: Creating a more defined profile and addressing mild jowl formation.
  • Under-Eye Rejuvenation: Strategically placed filler can reduce shadows and a tired appearance.
  • Hand Rejuvenation: Using fillers to restore volume to the back of the hands, hiding prominent veins and tendons.
Emily and a patient

What to Expect During Your Treatment

Your journey begins with a comprehensive consultation where Emily or Agnes will evaluate your facial anatomy and discuss your aesthetic goals. The actual injection process is relatively quick, often taking less than 30 minutes.

To ensure your comfort, we use various techniques, including topical numbing cream and fillers formulated with lidocaine. Most patients describe the sensation as a minor pinch. There is typically very little downtime, though some mild swelling or bruising at the injection sites may occur. Most minor side effects resolve within 7 to 14 days.

Procedure FAQs

Where can I find injectable dermal fillers near me?

If you are looking for high-quality injectable dermal fillers in the San Francisco Bay Area, the practice of Dr. Karen Horton offers a boutique, patient-centered experience. Our Board-Certified Nurse Practitioners provide personalized care designed to deliver subtle, natural-looking results in a safe and professional environment.

Can I combine any other treatments with dermal fillers?

Absolutely. Many of our patients choose to combine fillers with BOTOX® or other neuromodulators like Dysport® to address dynamic wrinkles like crow's feet. Additionally, fillers can be paired with skincare treatments such as Clear + Brilliant laser resurfacing or IPL skin rejuvenation to improve overall skin texture and tone.

How long do the results last?

The longevity of results depends on the specific filler used and the treatment area. Hyaluronic acid fillers typically last between 6 and 18 months, while Voluma XC can last up to two years.

Is there any downtime?

Most patients return to their normal activities immediately. We recommend avoiding strenuous exercise and excessive sun exposure for the first 24 to 48 hours to minimize swelling.

Meet Our Aesthetic Team

Emily Sespaniak, NP

Emily is a graduate of the University of Florida with a Master of Science in Nursing. She is Board-Certified by the American Nurses Credentialing Center (ANCC) and has over a decade of experience honing her skills as the lead injector at the practice. Winner of the “Best Medical Spa” category in the SFGATE Best of 2025 Awards, Emily is known for her “gentle injector” technique and commitment to preserving natural beauty.

Agnes Wong, MSN, NP-BC

Agnes holds a Master of Science in Nursing from SUNY Downstate Medical Center and is Board-Certified by the ANCC. With advanced training in facial anatomy and full-facial balancing, Agnes focuses on enhancing her patients’ unique features through precise, artistic injections.

Emily Sespaniak, NP and Agnes Wong, MSN, NP-BC

Our goal is always a noticeable result that is so natural that no one will know!

Find Out About Dr. Horton's Personal Aesthetics Routine!

Schedule Your Consultation in San Francisco

Ready to restore your youthful glow and achieve natural, balanced results? Whether you are interested in subtle lip enhancement, cheek contouring, or a full-facial rejuvenation, our Board-Certified Nurse Practitioners are here to guide you.

At the practice of Dr. Karen Horton, a Board-Certified Plastic Surgeon, we prioritize patient education and a gentle, meticulous approach to every treatment. During your personalized consultation, Emily or Agnes will evaluate your unique facial anatomy and develop a customized treatment plan tailored to your aesthetic goals.

To take the first step toward a refreshed and rejuvenated appearance, please complete our online consultation request form.

Dr. Karen Horton has either authored or reviewed and approved this content.

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Our Location

Hours

Monday-Friday: 9am - 5pm

Saturday-Sunday: Closed

Monday:
9 AM to 5 PM

Tuesday:
9 AM to 5 PM

Wednesday:
9 AM to 5 PM

Thursday:
9 AM to 5 PM

Friday:
9 AM to 5 PM

Saturday:
Closed

Sunday:
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Address

Dr. Karen M. Horton
2100 Webster St., Suite 520
San Francisco, CA 94115
Phone: 415.923.3067

We are located in the
Pacific Heights District
in the Pacific Professional Building.

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*Please note: Our office is no longer a Participating Provider for insurance. We can provide a financial quote for what anticipated surgical fees will be after your consultation.

Accreditations

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Castle Connolly Exceptional Women in Medicine award
Marin Magazine Top Doctors 2026 Award

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